FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, specifically to a method for the synthesis of 2- and 4-(1,3,5-dithiazinan-5-yl)-phenols of the general formula 
. The method involves a reaction between o- or n-aminophenol and 1,3,5-trithiane over ferric chloride hexahydrate as a catalyst [FeCl3*6H2O], the molar ratio of o-, n-aminophenol : 1,3,5-trithiane : FeCl3*6H2O = 10:(10-12):(0.3-0.7), in argon atmosphere, acetonitrile as a solvent at the temperature of 50-70°C and atmospheric pressure, the reaction duration is 5-7 hours.
EFFECT: improved method for the synthesis of 2- and 4-(1,3,5-dithiazinan-5-yl)-phenols enables to reduce the process toxicity.
1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING 2- AND 4-(1,3,5-DITHIAZINAN-5-YL)-PHENOLS | 2010 |
|
RU2443693C1 |
| METHOD OF PRODUCING N-ARYL-1,3,5-DITHIAZINANES | 2010 |
|
RU2443694C2 |
| METHOD FOR PREPARING (1,5,3-DITIAZEPINAN-3-YL)(THIO)PHENOLS | 2011 |
|
RU2478623C2 |
| METHOD OF OBTAINING 4-(1,5,3-DITHIAZEPINAN-3-YL)-BENZOIC AND 5-(1,5,3-DITHIAZEPINAN-3-YL)-2-HYDROXYBENZOIC ACIDS | 2012 |
|
RU2529516C2 |
| METHOD OF PRODUCING N-ARYL(BENZYL)-(1,3,5-DITHIAZIN-5-YL)AMINES | 2010 |
|
RU2464265C2 |
| METHOD OF OBTAINING 3,3'-(1,2-PHENYLENE)-BIS-1,5,3-DITHIAZEPINANE AND 3,3,-[METHYLENE-BIS-(1,4-PHENYLENE)]-BIS-1,5,3- DITHIAZEPINANE | 2011 |
|
RU2467006C1 |
| METHOD OF SELECTIVE OBTAINING 3,3'-[METHYLENEBIS(1,4-PHENYLENE)]-, 3,3'-[OXYBIS(1,4-PHENYLENE)]- AND 3,3'-(3,3'-DIMETHOXYBIPHENYL-4, 4'-DIYL)-BIS-1,5,3-DITHIAZEPINANES | 2012 |
|
RU2518485C2 |
| METHOD OF OBTAINING A, α,ω-BIS-(1, 5, 3-DITHIAZEPINAN-3-YL)ALKANES | 2011 |
|
RU2466999C1 |
| METHOD FOR PREPARING 2- AND 4-(1,5,3-DITHIAZOCYNAN-3-YL)PHENOLS | 2011 |
|
RU2478627C2 |
| METHOD FOR SELECTIVE PRODUCTION OF 3,3'-[BIS-(1,4-PHENYLENE)]BIS-1,3,5-DITHIAZINANES | 2012 |
|
RU2529509C2 |
