PHOTOSENSITISER AND METHOD FOR PRODUCING IT Russian patent published in 2015 - IPC A61K31/409 A61K47/36 A61P35/00 

FIELD: pharmacology.

SUBSTANCE: invention is applicable to produce lyophilised trismethyl glucamine salt of chlorine e6, which is used as a high-effective photosensitiser (PS) for the purpose of photodynamic therapy (PDT) of cancer and other new growths of various origins, as well as for fluorescent diagnosing of cancer cells. The method for producing the PDT photosensitiser involves dissolving methylfeoforbide in acetone, processing the produced solution with aqueous alkali NaOH or KOH, and neutralising the reaction mixture with diluted hydrochloric acid, separating precipitated chlorine e6, washing, processing the precipitation with aqueous solution and lyophilising. Implementing the invention enables eliminating pseudocolloidal precipitation, and producing fine and dense precipitation of the photosensitise low in foreign matters.

EFFECT: photosensitiser provides adequate cryostabilisation, reduced length of patient rehabilitation, more effective lysis of involved and tumour tissues.

2 cl, 2 ex