FIELD: medicine.
SUBSTANCE: inventions cover preparing the biologically active compounds of chlorine series -photosensitiser (PS) for photodynamic therapy (PDT). The PS contains chlorine e6 with N-methyl-D-glucamine and sodium in molar ratios as follows 1:2:1, and a cryostabiliser. The PS has structural formula (I): Also, th invention discloses the method for making the photosensitiser for photodynamic therapy according to which chlorine e6 is suspended in apyrogenic water; N-methyl-D-glucamine and sodium hydroxide (NaOH) are added in stirring. The prepared chlorine e6 salt solution is filtered with the cryostabiliser added in estimated amount, and lyophilised.
EFFECT: said PS shows prolonged storage-stability, improved service properties and the consumer appeal, extended storage life as a medical preparation.
4 cl, 1 ex, 1 tbl
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Authors
Dates
2009-09-20—Published
2008-04-22—Filed