FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to solid form, including crystalline compound of formula 1: or its pharmaceutically acceptable salt, hydrate or solvate. Crystalline compound of formula 1 represents crystalline form A of formula 1 and has X-ray powder diffractogram, containing peaks, in approximate peak positions: 17.26±0.10, 21.60±0.10 and 27.73±0.10 degrees 2θ and at least in approximate peak positions: 9.68±0.10, 24.68±0.10, 25.48±0.10 and 29/08±0.10 degrees 2θ. Also claimed are pharmaceutical compositions for treating FAAH-mediated condition, method of obtaining solid form, including crystalline compound of formula 1 or its pharmaceutically acceptable salt, hydrate or solvate, and method of treating FAAH-mediated condition.
EFFECT: invention makes it possible to obtain solid form, including crystalline compound of formula 1, useful for obtaining final drug forms with improved properties.
53 cl, 35 dwg, 5 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
NOVEL CRYSTALLINE FORMS OF SODIUM SALT OF (4-{4-[5-(6-TRIFLUOROMETHYL-PYRIDIN-3-YLAMINO)PYRIDIN-2-YL]PHENYL}CYCLOHEXYL) ACETIC ACID | 2011 |
|
RU2612556C2 |
CRYSTALLINE FORMS OF (R)-5-[3-CHLORO-4-(2, 3-DIHYDROXYPROPOXY)BEZ[Z]ILIDEN]-2-([Z]-PROPYLIMINO)-3-o-TOLYLTHIAZOLIDIN-4-ONE | 2009 |
|
RU2519548C2 |
PERIPHERALLY RESTRICTED FAAH INHIBITORS | 2011 |
|
RU2583435C2 |
SOLID FORMS OF 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS AND USE | 2012 |
|
RU2611007C2 |
ISOXAZOLINE AS FATTY ACID AMIDE HYDROLASE INHIBITORS | 2010 |
|
RU2539595C2 |
PHENYLCARBAMATES AND USE THEREOF AS ENZYME INHIBITORS OF HYDROLASES OF FATTY ACID AMIDES (FAAH) AND DOPAMINE RECEPTOR D3 (D3DR) MODULATORS | 2014 |
|
RU2693457C2 |
METHOD FOR OBTAINING MODULATORS OF CYSTIC FIBROUSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | 2010 |
|
RU2553989C2 |
CRYSTALLINE FORMS OF {[1-CYANO-5-(4-CHLOROPHENOXY)-4-HYDROXY-ISOQUINOLINE-3-CARBONYL]-AMINO}-ACETIC ACID | 2014 |
|
RU2666144C2 |
CRYSTALLINE FORM OF (-AMINOBUTYRIC ACID ANALOGUE | 2004 |
|
RU2412162C2 |
DOSAGE FORMS, SALTS AND POLYMORPHS OF TRANSNORSERTRALINE AND USING THEM | 2010 |
|
RU2578956C2 |
Authors
Dates
2015-11-20—Published
2011-02-01—Filed