METHOD FOR DETERMINING NECESSITY OF USING EXTRACORPOREAL OXYGENATION SUPPORT IN LUNG TRANSPLANTATION Russian patent published in 2015 - IPC A61B5/145 A61B5/205 A61M16/01 

FIELD: medicine.

SUBSTANCE: 10 minutes after artificial one-lung ventilation starts, before a lung is removed, partial pressure of oxygen arterial blood (PaO₂), arterial blood pH value (pH) and average pressure in the pulmonary artery are measured. That is combined with assessing the artificial one-lung ventilation parameters. Airway plateau pressure (Pplato) generated by an artificial lung ventilation apparatus and oxygen percentage in respiratory gas (FiO₂) supplied to the lungs are measured. The value (X) is calculated by formula: , wherein Z is an arterial blood pH level (pH) in points according to the following provisions: if pH is more than 7.3, the pH level is 0 points; if pH falls within the range from 7.3 to 7.25, the pH level is 5 points; pH from 7.24 to 7.2 stands for 10 points, and pH less than 7.2 requires 15 points; Y is an average pressure in the pulmonary artery (avPPA) in points according to the following provisions: if avPPA is less than 40 mm Hg, 0 points are assigned; avPPA from 40 to 50 mm provides 5 points; 10 points are added if avPPA is from 51 to 60 mm Hg, and avPPA exceeding 60 mm Hg means 15 points. If X is 35 or more, using the extracorporeal oxygenation techniques is considered to be unavoidable. If X is less than 35, it is supposed to be determined at the following transplantation stages.

EFFECT: method enables the accurate determination if it is necessary to start complete substitution of the pulmonary ventilation and to support the blood flow by means of extracorporeal membrane oxygenation during a lung transplantation surgery.

4 cl, 11 tbl, 3 ex