METHOD FOR OBTAINING KIDNEY TRANSPLANTS FROM DONORS WITH OUT-OF-HOSPITAL CIRCULATORY ARREST Russian patent published in 2024 - IPC A61B17/00 A61M60/104 A61B18/02 A61M5/00 A61M60/38 A61M1/36 

FIELD: medicine; transplantology; nephrology.

SUBSTANCE: invention can be used for treating patients with end-stage chronic renal failure. After biological death of the donor as a result of irreversible cardiac arrest, the automated chest compression device is continued before normothermic extracorporeal oxygenated perfusion of renal grafts. Femoral vessels of the donor are catheterised. Normothermic extracorporeal oxygenating perfusion of renal grafts is carried out at a flow rate of 2.4 l/min, temperature of 35.0 °C. After explantation of renal grafts, they are placed in sterile bags filled with a preserving solution, cold preservation is started. After the renal grafts are delivered to the transplantation center, machine oxygenated cold perfusion is started to achieve a target pressure of 30 mm Hg, which is completed at the moment of delivery of the recipient into the operating room and the beginning of the pre-transplantation preparation.

EFFECT: method enables preserving the kidneys in the donor’s body after the donor’s death, their explantation, the subsequent assessment of the donor’s kidney suitability for transplantation, reducing their ischemic damage and safe performance of transplantation with obtaining primary renal transplant function in recipient due to successive application of automated chest compression device, normothermic extracorporeal oxygenating perfusion of abdominal organs and machine oxygenated cold perfusion in donor.

1 cl, 4 dwg, 1 ex