FIELD: chemistry.
SUBSTANCE: invention relates to 3-acylaminopyridin-2(1H)-one and its novel derivatives, which can be potential medications for treatment of type II diabetes. , wherein X - -(CH2)n-n=0-2, -CH(OCH3)-, -CH=CH-; Y - 1-adamantyl, 4-isopropylphenyl,3-(methoxymethyl)-4-methoxyphenyl, 3-(4-methyl-1H-pyrazol-1-yl)methyl-4-methoxyphenyl, 4-(difluoromethoxy)phenyl, 3,5-dimethylisoxazol-4-yl, 3,5-dimethyl-4-nitro-1H-pyrazol-1-yl, 3-trifluoromethyl-1H-pyrazol-1-yl, 1-ethyl-3-trifluoromethyl-1H-pyrazol-5-yl, 1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl; Z - 4 pyridyl, bromine.
EFFECT: obtaining medication for treating diabetes.
4 cl, 2 dwg, 3 tbl, 21 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF TREATING DIABETES MELLITUS | 2019 |
|
RU2734495C1 |
DERIVATIVES OF 1,4-DIOXIDE OF QUINOXALINE-2-CARBONITRILE INHIBITING TUMOUR CELLS GROWTH | 2016 |
|
RU2640304C1 |
METHOD FOR INHIBITING TUMOR CELLS WITH NEW DERIVATIVES OF 3-TRIFLUOROMETHYLQUINOXALINE 1,4-DIOXIDE | 2020 |
|
RU2746395C1 |
OXOQUINAZOLINYL-BUTANAMIDE DERIVATIVES | 2014 |
|
RU2669393C2 |
2,8-BIS-(5-METHYLISOXAZOL-3-YL OR 1,5-DIMETHYL-3-OXO-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-4-YL)-2,3,8, 9,12c,12d-HEXAHYDRO-1H,7H-5,11-DIOXA-2,3a.4,6,6b8,9a,10,12,12b-DECAAZADICYCLOPENTA[e,l]PYRENES, METHOD FOR THEIR PRODUCTION AND APPLICATION IN AS A PRODUCT WITH CYTOTOXIC ACTIVITY | 2021 |
|
RU2785543C1 |
4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)-PYRIMIDINE DERIVATIVES | 2020 |
|
RU2822388C2 |
NEW ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE AND PHOSPHODIESTERASE INHIBITORS WITH DUAL ACTION MECHANISM AND THEIR APPLICATION | 2018 |
|
RU2758373C2 |
ARYLMETHOXY ISOINDOLIN DERIVATIVE, COMPOSITIONS INCLUDING THEREOF AND METHODS OF THEIR APPLICATION | 2011 |
|
RU2567753C2 |
ANTIBACTERIAL AGENTS BASED ON QUATERNARY AMMONIUM SALTS | 2014 |
|
RU2561281C1 |
BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | 2016 |
|
RU2738232C2 |
Authors
Dates
2015-12-20—Published
2013-10-21—Filed