SARM COMPOUNDS AND METHODS OF THEIR APPLICATION Russian patent published in 2015 - IPC C07C255/60 C07C235/24 A61K31/167 A23K1/22 

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to methods of influencing composition of animal carcass by introduction of acylanilide compounds of selective androgenic receptor modulators (SARM), represented by formula , where Z stands for NO₂, CN, Cl, F, Br or I; Y stands for CF₃, F, Br, Cl or I; R₂ stands for H, F, Cl, Br, I, CH₃, CF₃, OH, CN, NO₂, NHCOCH₃ or NHCOCF₃; R₃ stands for H; Q stands for H, halogen, CF₃ or CN; n=1; and m=1; or its isomer, pharmaceutically acceptable salt, crystal, N-oxide, hydrate or any their combination, where composition of carcass is subjected to impact by increase of fat-free mass, reduction of fat mass and/or reduction of percentage of fat mass; and where animals are represented by feedlot animals, beef cattle or fattening cattle. Impact on carcass composition in animals includes increase of growth indices, increase of average day gain (ADG) and increase of ratio forage:gain (F:G). Method includes feeding animals with such everyday forage, which contains formula IIIA compound.

EFFECT: improvement of meat production in fattening animals by increase of fat-free mass, reduction of fat mass and/or reduction of percentage of fat mass, increase of forage effectiveness and modulation of meat quality in animals, in feedlot animals or fattening cattle of beef cattle type or pigs.

13 cl, 26 dwg, 11 tbl, 20 ex