NOVEL CRYSTALLINE ACID-ADDITION SALTS OF TRICYCLIC DERIVATIVE OR THEIR HYDRATES AND METHOD FOR THEREOF OBTAINING Russian patent published in 2016 - IPC C07D471/04 C07D221/06 C07D413/06 A61K31/4375 A61P25/00

Abstract RU 2572820 C1

FIELD: chemistry.

SUBSTANCE: invention relates to novel crystalline acid-addition salt of tricyclic derivative in form of its hydrate, represented by the following chemical formula 2: , method for thereof obtaining, and based on its pharmaceutical composition for prevention and treatment of diseases, caused by PARP overactivity.

EFFECT: obtained is novel crustalline acid-addition salt of tricyclic derivative in form of its hydrate, which is stable with respect to hygroscopicity and therefore useful in supporting quality in medication obtaining.

4 cl, 3 dwg, 2 tbl, 22 ex

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RU 2 572 820 C1

Authors

E In-Khae

Park Chun-Kho

Choj Dzong-Khee

Kang Dong-Il

Dates

2016-01-20—Published

2013-01-28—Filed