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2 823 022

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IPC

C07K5/08(2006-01-01)

C07K5/87(2006-01-01)

A61K38/06(2006-01-01)

(21) (22)

Application

2023131687, 2023-12-04

(24)

Start date

2023-12-04

(22)

Actual filing date

2023-12-04

(45)

Published

2024-07-17

(72)

Inventor

Deeva Olga AlekseevnaMokrov Grigorij VladimirovichPantileev Andrej SergeevichPovarnina Polina YurevnaAntipova Tatyana AlekseevnaGudasheva Tatyana AleksandrovnaDorofeev Vladimir Lvovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Originalnykh I Perspektivnykh Biomeditsinskikh I Farmatsevticheskikh Tekhnologij"

TRIPEPTIDE HAVING NEUROPSYCHOTROPIC ACTIVITY Russian patent published in 2024 - IPC C07K5/08 C07K5/87 A61K38/06

Abstract RU 2823022 C1

FIELD: biotechnology.

SUBSTANCE: present invention relates to a novel biologically active peptide of formula: H-(L-Phe)-(L-Trp)-(L-Leu)-NH₂ (L-phenylalanyl-L-tryptophanyl-L-leucine amide). Invention discloses a tripeptide ligand of mitochondrial translocator protein (TSPO), having neuropsychotropic properties: anxiolytic, antidepressant and neuroprotective activities.

EFFECT: invention can be used in medicine as a fast-acting anxiolytic, antidepressant and neuroprotector for treating anxiety, anxiety and anxiety-depressive disorders.

1 cl, 2 dwg, 3 tbl, 5 ex

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RU 2 823 022 C1

Authors

Deeva Olga Alekseevna

Mokrov Grigorij Vladimirovich

Pantileev Andrej Sergeevich

Povarnina Polina Yurevna

Antipova Tatyana Alekseevna

Gudasheva Tatyana Aleksandrovna

Dorofeev Vladimir Lvovich

Dates

2024-07-17—Published

2023-12-04—Filed