FIELD: chemistry.
SUBSTANCE: invention relates to field of biotechnology. Method for separation of monomer antibody from composition, containing aggregates of antibodies with high molecular weight, includes contact of composition with hydroxyapatite resin and elution of purified antibody from resin.
EFFECT: methods make it possible to obtain composition, in which content of aggregates of antibodies with high molecular weight is reduced to 1%.
21 cl, 4 dwg, 14 tbl, 11 ex
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