FIELD: chemistry.
SUBSTANCE: invention relates to field of biochemistry. Claimed is method of gaseous substrate fermentation. Method includes supply of carbon monoxide-containing gaseous substrate into culture water medium in bioreactor, where said culture medium includes one or several anaerobic acetogenic microorganisms, increase of cell density by regulation of specific CO absorption by anaerobic acetogenic microorganisms in culture water medium, with rate of rate of change of specific CO absorption switching on regulation of CO supply rate, with regulation of CO supply rate switching on determination of CO supply rate, determination of CO discharge rate and determination of weight of cells. Change of specific CO absorption in the interval from 0.1 to 1.0 mmol/min/gram of dry cells. Supply of continuous water medium flow into bioreactor, discharge of continuous flow of fermentation broth from bioreactor, with said stages being repeated until required productivity by ethanol in the interval from 1 to 50 g/l is achieved.
EFFECT: invention provides increased density of cells in microbiological fermentation of gaseous substrate.
8 cl, 1 dwg, 1 tbl, 5 ex
