FIELD: chemistry.
SUBSTANCE: invention relates to conjugates, in particular presented is nicotine hapten-carrier of formula (III): 
W represents -O- and is in position 5 of pyridine ring; -(spacer)- represents C1-C8alkylene group, C3-C10cycloalkylene group or C1-C12alkylene group, interrupted by 1-4 oxygen atoms and possibly interrupted by group -N(H)C(O)-; X* represents -NH- or -S-; m stands for 1; n stands for integer number from 1 to 1000; and Y represents possibly modified carrier protein, selected from bacterial anatoxins, immunogenic substances, viruses, virus-like particles, protein complexes, proteins, polypeptides, liposomes and immunostimulating complexes, which can be used for preparation of vaccines for treatment and/or prevention of nicotine dependence.
EFFECT: obtaining compounds which can be used for preparation of vaccines for treatment and/or prevention of nicotine dependence.
8 cl, 23 dwg, 7 tbl, 22 ex
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