ANTI-PBP2A PROTEIN MONOCLONAL ANTIBODIES AND HOMOLOGOUS SEQUENCES FOR TREATING BACTERIAL INFECTION AND IMMUNODIAGNOSIS OF Firmicutes BACTERIA Russian patent published in 2016 - IPC C07K16/12 A61K39/40 

Abstract RU 2575070 C2

FIELD: chemistry.

SUBSTANCE: what is presented is a recovered monoclonal antibody, which binds to PBP2a or PBP5 protein. The above antibody contains a heavy chain variable region having CDR1 region, which includes SEQ ID NO: 12, CDR2 region, which includes SEQ ID NO: 13, CDR3 region, which includes SEQ ID NO: 14, and a light chain variable region having CDR1 region, which includes SEQ ID NO: 6, CDR2 region, which includes SEQ ID NO: 7, CDR3 region, which includes SEQ ID NO: 8. What is also presented is a pharmaceutical composition containing the above antibody.

EFFECT: group of inventions has immunising action on an infection caused by bacteria possessing PBP2a or PBP5 protein.

4 cl, 20 dwg, 3 tbl, 4 ex

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RU 2 575 070 C2

Authors

Senna Zhoze Prokopiu Moreno

Kejros Zhuan Luis Sampaja

Batoreu Nadia Maria

Tejshejra Marija Da Glorija Martins

Dates

2016-02-10Published

2010-08-10Filed