FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry, particularly to an anti-WTA (teichoic acid conjugate) antibody-antibiotic for treating Staphylococcus aureus bacterial infection, as well as to a pharmaceutical composition containing it. Also disclosed a method of producing an anti-WTA antibody-antibiotic conjugate involving conjugation of an intermediate antibiotic linker with an anti-WTA antibody.
EFFECT: invention provides effective treatment of bacterial infection caused by Staphylococcus aureus.
23 cl, 22 dwg, 24 ex, 5 tbl
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Authors
Dates
2019-05-06—Published
2014-05-22—Filed