ANTIBODIES AGAINST TEICHOIC ACID CONJUGATE AND THEIR CONJUGATES Russian patent published in 2019 - IPC C07K16/12 A61K39/395 

Abstract RU 2687044 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry, particularly to an anti-WTA (teichoic acid conjugate) antibody-antibiotic for treating Staphylococcus aureus bacterial infection, as well as to a pharmaceutical composition containing it. Also disclosed a method of producing an anti-WTA antibody-antibiotic conjugate involving conjugation of an intermediate antibiotic linker with an anti-WTA antibody.

EFFECT: invention provides effective treatment of bacterial infection caused by Staphylococcus aureus.

23 cl, 22 dwg, 24 ex, 5 tbl

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RU 2 687 044 C2

Authors

Brown Eric J.

Flygare John

Hazenbos Wouter

Lehar Sophie M.

Mariathasan Sanjeev

Morisaki John Hiroshi

Pillow Thomas H.

Staben Leanna

Vandlen Richard

Koefoed Klaus

Strandh Magnus

Andersen Peter S.

Dates

2019-05-06Published

2014-05-22Filed