METHOD FOR DETERMINING EFFECTIVENESS OF CONSERVATIVE TREATMENT OF CANCER OF UNENLARGED OVARIES Russian patent published in 2016 - IPC A61B8/08 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to functional diagnostics, and can be used to determine effectiveness of conservative treatment of cancer not enlarged ovaries. Abdominal ultrasound is performed. Method includes detecting occurrence of secondary metastatic changes, determining location of lower and side edges of affected greater omentum. Using a standard sensor for abdominal investigations with operating frequency 3.5 Mhz series of parallel crosswise cuts in mode of panoramic scanning from right to left edges of greater omentum with step - 0.5 cm from lower surface of transverse colon to lower edge of rendered changed greater omentum. Using a program for area measurement irregular formations, contained in apparatus, section area of greater omentum is measured on each of performed scans. Volume of the greater omentum is determined - V_prim. At stages of dynamic observation during conservative anticancer therapy previous algorithm of survey is repeated. Volume of the greater omentum is determined V_bis. Calculating efficiency coefficient K_eff of antineoplastic therapy according to formula: somewhere K_eff - effectiveness ratio of anticancer therapy, - V_bis - volume of greater omentum at stages in process of follow-conservative anti-tumor therapy, - V_prim - volume of greater omentum before course of conservative treatment, and if K_eff = 100 % - a large gland after treatment is not rendered - define complete tumor response to therapy; at K_eff, equal to or greater than 50 % - a partial response; at K_eff less than 50 % but more than 25 % - minimum response; at K_eff less than 25 %, absence of new lesions - stabilisation.

EFFECT: method enables to determine effectiveness of conservative treatment of ovarian cancer is not increased by a change in volume of affected omentum.

1 cl, 3 ex