FIELD: medicine.
SUBSTANCE: present invention describes a method of preventing and/or treating a wound infection by introducing to a wound a clear depot comprising at least two hydrophilic water-soluble pharmaceutically active agents selected from a group consisting of pharmaceutically acceptable salts of vancomycin, gentamicin, and a mixture thereof, water, a phospholipid, oil, a pH adjusting agent, and a viscosity modifying agent. Oil is selected from vegetable oils, animal fats and mixtures thereof. Viscosity modifying agent is selected from ethanol, isopropanol and mixtures thereof. Water content in viscous depot does not exceed 2 wt% of total weight of depot. Said depot is administered by subcutaneous or intramuscular injection or infusion or injection into wound. Said depot has a pH of 3 to 5.
EFFECT: viscous phospholipid depot according to invention is transparent and stable in storage.
10 cl, 9 dwg, 11 tbl, 9 ex
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