METHOD FOR PRODUCING INSTANT FORMULATION OF FURACILIN (OPTIONAL) Russian patent published in 2016 - IPC A61K31/345 A61K9/16 A61K9/20 A61K9/46 A61K47/32 

Abstract RU 2578456 C1

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions is a method for producing instant medicinal forms Furacilin: in the first embodiment, the mixture Furacilin and polyvinylpyrrolidone with a molecular weight of 10,000±2,000 at a ratio of 1:1-3 was dissolved in ethanol 1: 100-300 95±5°C, half of the resulting solution of sodium bicarbonate powder is granulated in a ratio of 1.0:34.0-34.5 Furacilin the total weight, the other half is granulated citric acid powder in a ratio of 1.0 to the total weight of 39.0-39.5 Furacilin , granules mixed 1.00:1.12-1.14 and tableted or packed in sealed packages; second embodiment Furacilin mixture and polyvinylpyrrolidone 1:1-3 were placed in 30-40% ethanol at a ratio of 1:9-12 at 95±5°C, half of the resulting slurry granulated powder of sodium hydrogen carbonate in a ratio of 1.00:2.58-2.60 Furacilin the total weight, the other half is granulated citric acid powder in a ratio of 1.00: 2,96-3,00 by weight Furacilin, granules mixed 1.00:1.05-1.10, tableted or packed in airtight packaging.

EFFECT: implementation of the group of inventions and provides a simplification of the application dosage forms Furacilin increases its bioavailability.

2 cl, 2 ex, 4 tbl

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RU 2 578 456 C1

Authors

Krasnjuk Ivan Ivanovich

Stepanova Olga Ivanovna

Beljatskaja Anastasija Vladimirovna

Krasnjuk Ivan Ivanovich

Krasnjuk Olga Valentinovna

Popkov Vladimir Andreevich

Reshetnjak Vladimir Jurevich

Bajdikova Irina Vladimirovna

Engashev Sergej Vladimirovich

Dates

2016-03-27Published

2014-12-29Filed