METHOD OF PRODUCING PYRIPYROPENE DERIVATIVES Russian patent published in 2016 - IPC C07D493/04 

Abstract RU 2578605 C2

FIELD: chemistry.

SUBSTANCE: invention relates to the method of producing the compound C: , which includes one- to three-step selective acylation of the hydroxyl group in the first position and in the eleventh position of the compound of formula B1: , with an acylating agent in a solvent selected from N-methyl-2-pyrrolidinone and N,N-dimethylacetamide, in the presence of a base selected from 2,4,6-collidine and 2,6-lutidine, or in the absence of a base.

EFFECT: method enables to selectively obtain the compound C with high output.

13 cl, 1 dwg, 5 tbl, 25 ex

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RU 2 578 605 C2

Authors

Fukuda Josimasa

Ando Takasi

Goto Kimikhiko

Nakanisi Nozomu

Vatanabe Takasi

Kurikhara Keniti

Minova Nobuto

Mitomi Masaaki

Dates

2016-03-27Published

2010-11-10Filed