FIELD: chemistry.
SUBSTANCE: invention relates to method of producing lutetium and gadolinium complexes with tetrabenzoporphyrin. Method involves reaction of phthalimide with zinc acetate at 230-240°C for 20-30 minutes. Obtained 1-[(oxo-1H-isoindol-3-yl)methylene]-isoindoline-3-on is melted with rare-earth element salt and sodium acetate trihydrate at temperature 350-360°C for 40-50 minutes. End products are separated and purified by chromatography.
EFFECT: technical result consists in reduced number of steps, increased output of end products and high degree of their purity.
1 cl, 4 dwg, 3 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCING TWO-DECK COMPLEX OF GADOLINIUM WITH TETRABENZOPORPHYRIN | 2017 |
|
RU2649402C1 |
| METHOD OF OBTAINING COMPLEXES OF LANTHANOIDS WITH 5, 15-DIPHENYLTETRABENZOPORINIC | 2016 |
|
RU2622292C1 |
| COMPLEXES OF 1-METHYLTETRABENZOOCTADEHYDROCORRIN WITH ZINC, COPPER AND HYDROXYLANTHANE | 2007 |
|
RU2360915C1 |
| ZINC 5,15-DIAMINOTETRABENZOPORPHYNATE | 2011 |
|
RU2454417C1 |
| METHOD FOR PRODUCING 3-(QUINOLINE-2-ILMETHYLENE) ISOINDOLIN-1-ONE | 2021 |
|
RU2803965C2 |
| METHOD FOR OBTAINING 2-[2-(2-METHOXYPHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE | 2022 |
|
RU2792273C1 |
| METHOD OF PRODUCING ZINC MESO-TETRA-AMINOTETRABENZOPORPHYRINATE | 2011 |
|
RU2458928C1 |
| ISOINDOLINONE INHIBITORS OF MDM2-P53 INTERACTION WITH ANTI-CANCER ACTIVITY | 2016 |
|
RU2794333C1 |
| METHOD OF OBTAINING ISOINDOLINE DERIVATIVES OR THEIR BASIC OR ACID SALTS | 0 |
|
SU638257A3 |
| ZINC MESO-TRANS-DIHEXADECYLTETRABENZOPORPHYRINATE | 2006 |
|
RU2326883C1 |
