METHOD FOR DIAGNOSIS OF DISTURBED ENERGY METABOLISM OF LYMPHOCYTES WITH COMMUNITY-ACQUIRED PNEUMONIA IN CHILDREN Russian patent published in 2016 - IPC G01N33/49 G01N33/53 

Abstract RU 2579317 C1

FIELD: medicine.

SUBSTANCE: invention can be used for assessing degree of breakdown of energy metabolism blood lymphocytes in children with community-acquired pneumonia (CAP). For this purpose, flow cytometry is used for accounting of lymphocytes with reduced membrane potential of mitochondria. With values from 0 to 35% normal level is diagnosed, 36 to 75% - subcompensated disorder, not requiring specific therapy, 76% and more - decompensated disorders requiring in complex treatment of community-acquired pneumonia assignment of en-ergotropic preparations.

EFFECT: using the given method enables detecting the disturbed cell supply at earlier stage, if no changes succinate dehydrogenase activity, which enables its use in clinical practice for separation of the risk groups of children with CAP requiring metabolic correction.

1 cl, 1 tbl, 4 ex

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RU 2 579 317 C1

Authors

Efimenko Marina Viktorovna

Li Ljudmila Alekseevna

Evseeva Galina Petrovna

Kozlov Vladimir Kirillovich

Dates

2016-04-10Published

2014-12-25Filed