FIELD: biotechnology.
SUBSTANCE: group of inventions is described, including a method for prediction of increase in sensitivity of tumour cells growth to Wnt inhibitor, an assay kit for cancer patient selection, for whom the favorable or not outcome can be achieved from therapeutic administration of a Wnt inhibitor, according to prediction. The prediction method includes the steps of: biomarker level determination in a tumour cell sample obtained from a subject; comparison of the biomarker level in a tumour cell sample withthe control biomarker level; selection of a subject who, according to the prediction, should have a favorable outcome from therapeutic administration of a Wnt inhibitor.
EFFECT: invention expands the arsenal of methods for tumour cells growth prediction.
25 cl, 8 dwg, 10 tbl, 4 ex
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Authors
Dates
2017-11-17—Published
2013-02-22—Filed