FIELD: medicine.
SUBSTANCE: invention relates to oncohematology, and can be used for prediction of recurrence free survival developing in patients with multiple myeloma after autologous hematopoietic stem cells. Method for prediction of recurrence free survival in patients with multiple myeloma following autologous transplantation of hematopoietic stem cells (ATGSK) includes flow cytometry and estimation of relative content of one of lymphocyte populations using its threshold value. Proposed method after apheresis procedure, before transplantation in patient's apheresis product relative number of CD45+CD19+ b-cells is determined, and if CD45+CD19+ b-cell count is more than 2.5%, shorter period-free survival after ATGSK is predicted, and if CD45+CD19+ b-cells count is less than 2.5%, extended recurrence free survival period after ATGSK is predicted.
EFFECT: simplified method for prediction of recurrence-free survival in patients with multiple myeloma after ATGSK.
1 cl, 1 dwg
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