FIELD: pharmacology.
SUBSTANCE: present invention is related to metered dose inhalation formulas and manufacturing process. The active pharmaceutical ingredient can be a beta-2-agonists, corticosteroids or a combination thereof.
EFFECT: inhalation formulas are homogenized suspensions with hydrofluoroalkane (HFA) propellant, minimal amount of ethanol 0 5/100 to 10 % (wt/wt%) and polyetheleneglycol (PEG) as suspending and particle size modifying agents.
20 cl, 11 ex, 8 dwg
Authors
Dates
2016-04-20—Published
2012-02-14—Filed