METHOD FOR RAPID DIAGNOSIS AND SCREENING OF GENERAL AND ORGAN HUMAN HOMEOSTASIS Russian patent published in 2016 - IPC G01N33/49 B82Y35/00 

Abstract RU 2583833 C2

FIELD: medicine.

SUBSTANCE: invention relates to laboratory diagnostics, and can be used for investigation of disturbed microcirculation system in human body based on investigation of blood and/or lymph nano-structures using laser correlation spectroscopy technique. For this purpose, blood volume is taken from vein, artery, lymph from lymphatic vessels or lymph nodes and blood corpuscles and/or lymph are separated, Zeta-potential and dimensional factors of dispersed phase of blood and lymph plasma nano-particles are measured by laser correlation spectroscopy analysers or only Zeta-potential of blood and lymph plasma measured without parallel measurement of parameters, values of studied Zeta-potential in millivolts and values of dimensional factors nano-particles dispersed phase of blood and lymph plasma by comparing obtained values of Zeta-potential and value of dimension factors of nano-particles of disperse phases of blood and/or lymph plasma with their normal values within range of allowable deviations. At that, in case of Zeta-potential deviations from normal values diagnostics of organism in outpatient or hospital environment is conducted in order to detect pathology, degree of manifestation and localisation. At that, in human of middle age in normal physiological conditions, on empty stomach Zeta-potential values of ζ ≤ -35 mV indicates high potential of transport mediums of body and absence of systemic disturbed microcirculation, Zeta-potential values -35 mV < ζ ≤ -27 mV testifies about normal (healthy) state of body transport mediums; Zeta-potential values -27 mV < ζ ≤ -10 mV testifies on boundary condition of body transport mediums requiring to specify reasons that caused such values of Zeta-potential; Zeta-potential in range of -10 mV < ζ ≤ +5 mV testifies on systemic violations of microcirculation.

EFFECT: invention enables diagnosing condition of total and/or organ homeostasis of human body as result of systematic disturbances of microcirculation in body.

2 cl, 6 dwg, 3 tbl

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RU 2 583 833 C2

Authors

Rozhkov Aleksandr Georgievich

Karandin Valerij Ivanovich

Danilin Aleksandr Nikolaevich

Dates

2016-05-10Published

2014-04-23Filed