METHOD FOR TREATING ATHEROSCLEROSIS Russian patent published in 2007 - IPC A61M1/34 

FIELD: medicine.

SUBSTANCE: the present innovation deals with the methods of cyclic extracorporal lymph purification against low-density cholesterol-lipoproteides (LDCL) and could be applied in treating patients in case of atherosclerotic vascular lesion. The first lymph portion should be withdrawn out of thoracic lymph duct by gravity into the external tank to be guided onto immunosorbent, moreover, simultaneously it is necessary to sample the next portion. Then the purified first portion should be returned by drops into one of the main veins of a patient and the second comes onto immunosorbent along with accumulating the third portion in the tank. The cycles ends on returning the purified third portion into one of the main veins. Moreover, period of time necessary for every stage of lymph purification upon immunosorbent should be prolonged by 20-40%. After that the following solutions should be passed through immunosorbent: glycine-HCl buffer at pH 2.5, phosphate buffer at pH 7.4 and physiological solution. The procedure mentioned should be carried out for about 7-10 d at the background of the diet at daily caloricity being up to 1500 kcal and sharp restriction of fats and carbohydrates. The innovation enables to withdraw LDCL out of lymph till their entering the circulation that prevents the contact of LDCL with hepatocytes and protein hydrolysis at developing free cholesterol and decreases damaging action of LDCL upon vascular endothelium.

EFFECT: higher efficiency of therapy.

2 cl, 3 dwg