FIELD: medicine.
SUBSTANCE: invention relates to medicine, specifically to cardiology, and can be used for prediction of increasing arterial stiffness in patients with high and very high cardiovascular risk and receiving statin therapy. Task is solved by determining in blood serum secretory phospholipase A2 (sPLA2) before beginning statin therapy. At initial value of patient's blood serum sPLA2 equal 7.69 ng/ml or higher, a higher arterial stiffness is predicted for 6 months from beginning of statin therapy. At initial value sPLA2 equal 4.09 ng/ml or less, absence of increasing arterial stiffness is predicted for 6 months of statin therapy.
EFFECT: proposed method allows predicting high arterial stiffness in given group of patients by using a new blood biomarker correcting therapy and reduce residual cardiovascular risk.
1 cl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING THE INDIVIDUAL RISK OF INCREASING THE CARDIO-MALLEOLAR VASCULAR STRESS COMPLEX IN 6 MONTHS FROM THE START OF LIPID-LOWERING THERAPY | 2018 |
|
RU2680141C1 |
| METHOD FOR DETERMINING DIAGNOSTIC CRITERION OF VASCULAR WALL STIFFNESS IN PATIENTS SUFFERING ARTERIAL HYPERTENSION ACCOMPANIED BY ABDOMINAL OBESITY | 2014 |
|
RU2567606C1 |
| METHOD OF PREDICTING RISK OF DEVELOPMENT OF ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES WITH PRIOR CORONARY ARTERY STENTING | 2015 |
|
RU2582291C1 |
| METHOD FOR PREDICTING THE RISK OF PROGRESSION OF PRIMARY OPEN-ANGLE GLAUCOMA | 2023 |
|
RU2804591C1 |
| METHOD FOR PREDICTING THE LEVEL OF CARDIO-ANKLE VASCULAR INDEX IN PATIENTS WITH DIABETES OF TYPE 2 IN COMBINATION WITH ARTERIAL HYPERTENSION AND ISCHEMIC HEART DISEASE | 2017 |
|
RU2656535C1 |
| METHOD OF PREDICTING PRESENCE OF ARTERIAL HYPERTENSION IN MEN WITH LOW OR MODERATE CARDIOVASCULAR RISK | 2023 |
|
RU2813029C1 |
| METHOD OF ESTIMATING RISK OF DEVELOPMENT OF UNFAVOURABLE CARDIOVASCULAR EVENTS IN PATIENTS WITH ISCHEMIC HEART DISEASE SUBJECTED TO ENDOVASCULAR MYOCARDIUM REVASCULARISATION DURING ONE YEAR AFTER INTERFERENCE | 2010 |
|
RU2444297C1 |
| METHOD FOR CORRECTION OF LIPOPEROXIDATION ACCOMPANYING HYPOLIPIDEMIC THERAPY OF PATIENTS WITH METABOLIC SYNDROME | 2011 |
|
RU2458687C1 |
| METHOD FOR PREDICTING VERY HIGH RISK OF CARDIOVASCULAR DISEASE IN MEN AGED 40-60 YEARS IN EUROPEAN POPULATION | 2020 |
|
RU2748715C1 |
| A METHOD FOR PREDICTING THE RISK OF ATHEROSCLEROSIS OF THE CAROTID ARTERIES IN PEOPLE 30-49 YEARS OF SLAVIC AND KOREAN ETHNICITY | 2022 |
|
RU2787738C1 |
