FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to oncology, and can be used in treating rectal cancer. 5-fluorouracil chemotherapy is carried out for 4-6 hours before gamma-therapy sessions enlarged fractions at 4 Gy according to dynamic dose fractionation for the first 3 days. At that, hydrogel tissue is used with 5-fluorouracil and sodium alginate “Coletex-5-ftur”, in which is added calcium sulfuric-acid in ratio 99.5-99.7 wt%: 0.5-0.3 wt%. Obtained mixture is formed in form of disc with diameter of 20-25 mm, thickness of 5-7 mm. Disc is fixed on distal end of faleic catheter. Then catheter is inserted in rectum, formed disk is located at level of tumour centre. Then air is fed into catheter cylinder till its complete filling and fixing in intestinal lumen. Catheter is removed before session of gamma-therapy.
EFFECT: method provides manifested regress of primary tumour that enables further carry out organ-preserving radical surgical intervention.
1 cl, 2 ex
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Authors
Dates
2016-06-10—Published
2015-06-09—Filed