COMPOSITIONS CONTAINING S-ADENOSYLMETHIONINE, AND ETHERS OF GALLIC ACID Russian patent published in 2016 - IPC A61K31/7076 A61K31/235 A61P43/00 

Abstract RU 2586300 C1

FIELD: medicine.

SUBSTANCE: proposed is an oral composition for the treatment of diseases and / or disorders that can be treated with S-adenosyl-L-methionine. Composition contains S-adenosyl-L-methionine (SAM-e or SAMe) and one or more esters of gallic acid selected from ethylgallate, isoamylgallate, propylgallate and octylgallate, the ratio (weight: weight) of the ester of gallic acid to S-adenosylmethionine ranges from 1:1 to 1:80.

EFFECT: technical result consists in improving delivery of SAMe, in particular an increase in SAMe concentrations in the plasma and the area under the curve of a pharmaceutical (AUC) SAMe.

8 cl, 3 dwg, 5 tbl

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RU 2 586 300 C1

Authors

Guan Dechi

Macdonald David I.

Dates

2016-06-10Published

2013-10-16Filed