FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to compositions of quinolinone derivatives, methods of obtaining and application of such compositions. Pharmaceutical composition contains lactate of compound 4-amino-5-fluorine-3-[6-(4-methylliperazine-1-yl)-1H-benzimidazole-2-yl]-1H-quinoline-2-one, or its tautomer or their mixture, in quantity from 10 to 80 wt % and at least one ingredient, selected from group, which includes (I) cellulose; (II) silicon dioxide; (III) magnesium stearate and (IV) ingredient, selected from crospovidone, starch and lactose. Composition is included in composition of capsule or pill.
EFFECT: compositions according to invention demonstrate satisfactory properties relating to rates of solution and stability.
49 cl, 2 dwg, 21 tbl, 12 ex
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