2-(R-THIO)-10-[3-(4-R-PIPERAZINE-1-YL)PROPYL]-10H-PHENOTHIAZINE FOR TREATING A BETA-AMYLOIDOSES OR ALPHA-SYNUCLEOPATHY AND METHOD FOR DIAGNOSIS OR PREDIAGNOSIS THEREOF Russian patent published in 2016 - IPC C07D417/06 C07D417/14 A61K31/5415 A61P25/28 

Abstract RU 2587154 C2

FIELD: medicine.

SUBSTANCE: invention relates to use of 2-(R2-thio)-10-[3-(4-R1-piperazin-1-yl)propyl]-10H-phenothiazine according to general formula I for treating a β-amyloidopathy or α-synucle- opathy followed by a cerebral protein deposit and reduced activity of cerebral ABCC1-transporter, including Alzheimer's dementia, Parkinson's disease or Lewy body dementia. According to general formula I R1 - Methyl group, R2 - Ethyl group, R3 - Hydrogen and R7 - Hydrogen.

EFFECT: treatment of β-amyloidopathy or α-synucleopathy.

3 cl, 12 dwg

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RU 2 587 154 C2

Authors

Panke Jens

Dates

2016-06-20Published

2011-08-30Filed