METHOD OF DETERMINING CHARACTERISTICS OF CIRCADIAN RHYTHM OF SUBJECT Russian patent published in 2016 - IPC A61B5/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely cardiovascular diagnostics. Readings are determined of first input signal showing cardiac function of individual for period of time T to obtain, as result, row of values x′_n of first input signal. Determined samples of second input signal showing activity of individual for period of time, overlapping period T of time to obtain, as result, row of values x_n of second input signal. Then series of values y_n is calculated of output signal from values x_n of first input signal and values x_n of second input signal according to model of autoregressive moving average (ARMAX). Values x′_n of first input signal and values x_n of the second input signal are used as exogenous input data. Value y_n of output signal for any n is calculated by linear combination of values x_n of first input signal and values x_n of second input signal. Periodic output signal is removed from calculated row of values y_n of output signal by harmonic regression analysis. Vibration parameter is then determined as characteristics of circadian rhythm.

EFFECT: method enables providing reliable assessment of parameters of oscillations of central driver circadian rhythm through analysis of cardiac function of subject, eliminating masking effects of endogenous circadian rhythm.

9 cl, 1 dwg