FIELD: medicine.
SUBSTANCE: disclosed is a group of inventions relates to treatment of malignant tumours. Disclosed are: use of 2-amide-1-({4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)pyridin-4-yl]thiazol-2-yl}amide) (S)-pyrrolidine-1,2-dicarboxylic acid or its salt for production of pharmaceutical compositions for treating a malignant tumour, combination of said compound with EGFR-modulators for said use, method of treating said disease using said compound and pharmaceutical compositions for treating said disease.
EFFECT: technical result is shown tumour regression under action of disclosed compound, synergetic anti-cancer action of said compound in combination with EGFR-modulator.
10 cl, 7 dwg, 3 tbl, 6 ex
