FIELD: chemistry.
SUBSTANCE: invention relates to polymer materials and specifically to a method of producing granules of cross-linked chitosan, which involves cross-linking chitosan with glutaric aldehyde using hydrochloric acid solution containing glutaric aldehyde, with molar ratio of chitosan:hydrochloric acid:glutaric aldehyde, equal to 1:(0.5-1.0):(0.1-1.0), and then extrusion moulding gel in form of threads, which are mechanically cut into granules and dried at temperature 40-70 °C for 1-2 hours.
EFFECT: invention provides decrease in method of amounts of acid, glutaric aldehyde and precipitation agents, enables to obtain chitosan granules of controlled size.
1 cl, 6 ex
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Authors
Dates
2016-07-10—Published
2015-06-29—Filed