FIELD: biochemistry.
SUBSTANCE: group of inventions relates to biochemistry. Invention discloses compound and versions of library of compounds for identification with required properties of compounds. Compound has formula
where each of n, m and p independently assumes values from 1 to 20; X is functional fragment, containing one or more structural elements; Z is oligonucleotide attached at its 3'-end to phosphate group; Y is oligonucleotide attached at its 5'-end to phosphate group. Also disclosed is a library for identifying with required properties of compounds containing a plurality of compounds of the said formula.
EFFECT: in another version library contains at least 102 differing above compounds, which contain functionally connected to oligonucleotide functional fragment consisting of two or more structural elements.
13 cl, 13 dwg, 7 tbl, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMPOUND CONTAINING CODING OLIGONUCLEOTIDE, PRODUCTION METHOD THEREOF, LIBRARY OF COMPOUNDS, PRODUCTION METHOD THEREOF, METHOD OF IDENTIFYING COMPOUND BOUND WITH BIOLOGICAL TARGET (VERSIONS) | 2006 |
|
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| BIOLOGICALLY ACTIVE COMPOUND CONTAINING CODING OLIGONUCLEOTIDE (VERSIONS), METHOD FOR SYNTHESIS THEREOF, LIBRARY OF COMPOUNDS (VERSIONS), METHOD FOR SYNTHESIS THEREOF, AND METHOD OF SEARCHING FOR COMPOUND BOUND WITH BIOLOGICAL TARGET (VERSIONS) | 2004 |
|
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|
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| METHOD FOR IDENTIFYING NATIVE PAIRS OF DNA OR RNA FRAGMENTS IN SAME LIVING CELLS | 2013 |
|
RU2578009C2 |
| ANALYSIS SYSTEM FOR ORTHOGONAL ACCESS TO BIOMOLECULES AND THEIR LABELLING IN CELL COMPARTMENTS | 2017 |
|
RU2771892C2 |
| TRANSPOSITION WITH PRESERVATION OF GENE ADHESION | 2015 |
|
RU2709655C2 |
| METHOD OF IDENTIFYING NATIVE PAIRS OF DNA OR RNA FRAGMENTS PRESENT IN THE SAME LIVING CELLS | 2015 |
|
RU2600873C1 |
| METHOD AND COMPOSITION FOR ANALYSIS OF CELLULAR COMPONENTS | 2016 |
|
RU2761432C2 |
| ISOLATED DNA MOLECULE ENCODING GLUCAGON RECEPTOR, DNA-CONSTRUCTION, CELL LINE, METHOD OF PREPARING GLUCAGON RECEPTOR, ISOLATED GLUCAGON RECEPTOR PEPTIDE, ISOLATED ANTIBODY, PROBE, METHOD OF DETECTION OF GLUCAGON ANTAGONIST PRESENCE | 1993 |
|
RU2184779C2 |
