BIOLOGICALLY ACTIVE COMPOUND CONTAINING CODING OLIGONUCLEOTIDE AND LIBRARY OF COMPOUNDS Russian patent published in 2016 - IPC C40B40/06 C07H21/00 

Abstract RU 2592673 C2

FIELD: biochemistry.

SUBSTANCE: group of inventions relates to biochemistry. Invention discloses compound and versions of library of compounds for identification with required properties of compounds. Compound has formula

where each of n, m and p independently assumes values from 1 to 20; X is functional fragment, containing one or more structural elements; Z is oligonucleotide attached at its 3'-end to phosphate group; Y is oligonucleotide attached at its 5'-end to phosphate group. Also disclosed is a library for identifying with required properties of compounds containing a plurality of compounds of the said formula.

EFFECT: in another version library contains at least 102 differing above compounds, which contain functionally connected to oligonucleotide functional fragment consisting of two or more structural elements.

13 cl, 13 dwg, 7 tbl, 10 ex

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RU 2 592 673 C2

Authors

Ariko-Muendel Kristofer K.

Acharya Raksha A.

Bendzhamin Denis

Vagner Richard

Dzhefter Malkolm L.

Izrael Devid I.

Kavarna Malkolm Dzh.

Klark Metyu

Krizer Stefan Filip

Chentrella Paolo A.

Morgan Berri

Frenklin Dzhordzh Dzh.

Khansen Nils Yakob Vest

Khejl Stiven

Dates

2016-07-27Published

2011-08-22Filed