FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, in particular to a system and methods for enhancing access to nuclear information molecules, such as DNA, RNA and proteins, using analytical biomolecules, such as transposomal complexes, by means of processing nuclei with a nuclear permeability enhancer, as well as to methods for using nuclear membrane, cell membrane and external compartmentalization approaches as proximity-preserving elements.
EFFECT: obtaining an analysis system for orthogonal access to biomolecules and their labeling in cell compartments.
33 cl, 11 dwg, 5 tbl, 13 ex
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