METHOD OF PRODUCING RADIOPHARMACEUTICAL PREPARATION "ASTATINE-211" Russian patent published in 2016 - IPC A61K101/00 A61P35/00 

Abstract RU 2593017 C1

FIELD: chemistry; medicine.

SUBSTANCE: present invention relates to conversion of chemical elements and radiation sources for medical purposes, particularly to a method of producing radiopharmaceutical preparation “Astatine-211” from an irradiated target, which includes subliming radionuclide at temperature 700÷850 °C for 4÷6 minutes, with its deposition in low-alkali buffer saline solution with pH 7.5-9, where target is Bi of natural isotopic composition that is irradiated by αparticles with energy 29÷31 MeV.

EFFECT: invention provides considerable reduction of time for obtaining stable forms of 211At, trophic to thyroid gland, reduction of radiation exposures on personnel, involved in manufacturing of preparation, and increased efficiency of synthesis of preparation.

1 cl, 1 dwg, 5 ex

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RU 2 593 017 C1

Authors

Yuminov Oleg Arkadevich

Drozdov Vadim Aleksandrovich

Eremenko Dmitrij Olegovich

Platonov Sergej Yurevich

Fotina Olga Vladilenovna

Dates

2016-07-27Published

2015-04-23Filed