METHOD OF PRODUCING TERBIUM-149 RADIOISOTOPE Russian patent published in 2016 - IPC G21G1/10 

FIELD: medicine; physics.

SUBSTANCE: invention relates to a method of producing ¹⁴⁹Tb radionuclide, used in nuclear medicine. Method comprises irradiation of the target of metal europium or its compounds on charged particle accelerator by light nuclei ³He (or ⁴He) and operating time in the target as a result of nuclear reactions ¹⁵¹Eu(³He,⁵n)¹⁴⁹Tb and (or) ¹⁵³Eu(³He, 7n)¹⁴⁹Tb (or, respectively, ¹⁵¹Eu(⁴He, 6n)¹⁴⁹Tb and (or) ¹⁵³Eu(⁴He, 8n)¹⁴⁹Tb) of radionuclide ¹⁴⁹Tb, which is removed from the target after irradiation by solid-state extraction, or by electromagnetic separation of isotopes.

EFFECT: possibility of using metal europium or its compounds of natural isotopic composition as the target material, possibility to use for producing ¹⁴⁹Tb relative to accelerators ⁴He and ³He of average energies, possibility to use for extracting ¹⁴⁹Tb without carrier by extraction chromatography or electromagnetic separation of isotopes, possibility to ensure ¹⁴⁹Tb output, acceptable for carrying out preclinical and clinical studies, and for further use.

3 cl, 2 tbl, 2 ex