COMBINATIONS OF MENINGOCOCCAL FACTOR-H-BINDING PROTEIN AND PNEUMOCOCCAL SACCHARIDE CONJUGATES Russian patent published in 2015 - IPC A61K39/02 

FIELD: chemistry.

SUBSTANCE: invention relates to biotechnology and immunology and represents an immunogenic composition for the activation of the immune response with respect to pneumococci and/or meningococci, which contains: (i) a mixture of conjugated pneumococcal capsular saccharides; and (ii) two different polypeptides of a factor-H-binding protein antigen (fHBP), but does not contain vesicles of the meningococcus outer membrane. The invention also relates to a method of activating the immune response in mammals with respect to pneumococci and/or meningococci, which includes the introduction of the said composition to a mammal.

EFFECT: invention makes it possible to extend the arsenal of combined vaccines with respect to pneumococci and/or meningococci.

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