METHOD FOR PRODUCTION OF SOLID DISPERSE SYSTEM WITH SILICON DIOXIDE Russian patent published in 2016 - IPC C01B33/00 C30B29/06 A61K9/10 A61K47/30

Abstract RU 2595846 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to medicinal agents, concerns preparation of dosage forms on basis of silicon dioxide. Task is solved by that mixer is filled mesoporous silicon dioxide, feeding into reactor an absorbable solution or melt of medicinal and auxiliary substances and intensely stirring for 5-7 minutes. Bulk product is formed with virtually 100 % yield and absence of losses. Flow rate of initial powder, as well as their compositions with auxiliary substances are assessed by rate of precipitation of powder or granules using a vibration funnel of serial device VP-12A with diameter of outlet hole 12 mm.

EFFECT: frequency and amplitude of vibration of vibration funnel is 50 Hz and 0, 08 mm, respectively.

1 cl, 5 ex, 2 tbl

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RU 2 595 846 C1

Authors

Suldin Aleksandr Vladimirovich

Dates

2016-08-27—Published

2015-04-27—Filed