FIELD: medicine.
SUBSTANCE: invention relates to medicine, specifically to immunology, and can be used for differential diagnosis of primary and secondary immune response to epidemic parotitis virus. Separation of types of immune response into primary and secondary is performed on basis of calculated using ROC analysis thresholds for IgG1 and IgG3 subclasses based on results of determining amount of specific mumps antibodies belonging to IgG1 and IgG3 subclasses by ELISA analysis. For threshold values of IgG1 < 55 % and IgG3 > 37.3 % of total amount of mumps IgG-antibodies primary immune response is diagnosed. For threshold values of IgG1> 55% and IgG3 < 37.3 % of total amount of mumps IgG-antibodies secondary immune response is diagnosed.
EFFECT: using the given method enables performing differential diagnosis of primary and secondary immune response to epidemic parotitis virus, that in turn enables detection of a group of primary infected by epidemic parotitis virus with threatening of orchitis sequelae.
1 cl, 3 tbl
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