URACIL OR THYMINE DERIVATIVES FOR TREATING HEPATITIS C Russian patent published in 2016 - IPC C07D239/22 C07D239/54 C07D401/10 C07D403/10 C07D409/10 C07D413/10 C07D417/10 A61K31/513 A61P31/12 

Abstract RU 2599635 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of N-(6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalene-2-yl)methanesulfonamide or its pharmaceutically acceptable salt for use as a medicinal agent for inhibiting replication of hepatitis C virus (HCV), as well as to a medicinal agent containing a therapeutically effective amount of the said compound or its pharmaceutically acceptable salt.

EFFECT: technical result is stable indices of efficiency of treating, relieving symptoms of hepatitis C, providing partial or complete reduction of symptoms.

5 cl, 46 dwg, 40 tbl, 140 ex

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RU 2 599 635 C2

Authors

Vagner Rolf

Tufano Majkl D.

Styuart Kent D.

Rokvej Todd V.

Rendolf Dzhon T.

Pratt Dzhon K.

Motter Kristofer E.

Maring Klarens Zh.

Lonzheneker Kenton L.

Liu Yaya

Liu Dakkhan

Kryuger Alan S.

Kati Varen M.

Khatchinson Duglas K.

Khuang Peggi P.

Flentzh Charlz A.

Donner Pamela L.

Degoj Devid A.

Betebenner Devid A.

Barnes Devid M.

Chen Shuang

Franktsik Ii Tadeus S.

Gao Ji

Khajt Entoni R.

Khengeveld Dzhon E.

Genri Rodzher F.

Koteki Brayan Zh.

Lou Ksiyaochun

Sarris Kati

Tsang Geoff G.Z.

Dates

2016-10-10Published

2013-02-01Filed