DOXORUBICIN AND ORGANOSILICON NANOPARTICLES-NIOSOMES- BASED PHARMACEUTICAL GEL FOR SKIN CANCER TREATING Russian patent published in 2016 - IPC A61K9/10 A61K9/51 A61K31/704 A61K47/24 A61P35/00 

Abstract RU 2600164 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine and represents a pharmaceutical anticancer gel containing 0.5 g of doxorubicin, 100 ml of PEG-12 dimethicone, 50 ml of gelling agent, 20 ml of triethanolamine and purified water - to 1,000.0 ml. Gel contains doxorubicin, encapsulated in niosomes formed by PEG-12 dimethicone.

EFFECT: technical result is higher efficiency of doxorubicin and reduced cardiotoxicity due to encapsulation in niosomes.

1 cl, 1 tbl, 5 dwg

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RU 2 600 164 C2

Authors

Bazikov Igor Aleksandrovich

Dates

2016-10-20Published

2014-11-17Filed