USE OF INVERSE AGONISTS OR ANTAGONISTS OF GHRELIN RECEPTOR FOR TREATING SLEEP DISORDERS Russian patent published in 2016 - IPC A61K31/397 A61K31/506 A61P25/20 

Abstract RU 2600895 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, specifically to neurology, and can be used for treating primary sleep disorder. Patient is administered a therapeutically effective amount of (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3,5]nonan-7-yl)ethanone or its pharmaceutically acceptable salt or a pharmaceutical composition containing therapeutically effective amount of (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3,5]nonan-7-yl)ethanone or its pharmaceutically acceptable salt and at least one pharmaceutically acceptable carrier, diluent or excipient.

EFFECT: group of inventions provides earlier sleep start time and considerable increase of its duration, as well as reduction of appetite.

4 cl, 6 dwg, 2 tbl

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RU 2 600 895 C2

Authors

Denney William S.

Jackson Margaret

Sonnenberg Gabriele

Dates

2016-10-27Published

2013-05-21Filed