FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, specifically to neurology, and can be used for treating primary sleep disorder. Patient is administered a therapeutically effective amount of (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3,5]nonan-7-yl)ethanone or its pharmaceutically acceptable salt or a pharmaceutical composition containing therapeutically effective amount of (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3,5]nonan-7-yl)ethanone or its pharmaceutically acceptable salt and at least one pharmaceutically acceptable carrier, diluent or excipient.
EFFECT: group of inventions provides earlier sleep start time and considerable increase of its duration, as well as reduction of appetite.
4 cl, 6 dwg, 2 tbl
Title | Year | Author | Number |
---|---|---|---|
2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3,5]NONANE DERIVATIVES AND USE THEREOF AS GHRELIN RECEPTOR ANTAGONISTS OR INVERSE AGONISTS | 2011 |
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Authors
Dates
2016-10-27—Published
2013-05-21—Filed