3-BENZOFURANYLINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3, PREPARING AND USING THEM IN THERAPY Russian patent published in 2015 - IPC C07D405/14 A61K31/496 A61P3/00

Abstract RU 2542991 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new 3-benzofuranylindol-2-one derivatives substituted in position 3 of formula wherein: R1 means a hydrogen atom; R2, R3, R4 equal or different, found in any accessible position of the phenyl ring, means independently a hydrogen atom or a halogen atom; R5 means (C1-6) alkyl group; n means 1; in the form of the base or acid-additive salt, as well as to a therapeutic agent and a pharmaceutical composition based on the above compounds possessing the ghrelin receptor antagonist activity, and to using this compounds for preparing the therapeutic agent for preventing or treating obesity, diabetes, appetite disorders and overweight.

EFFECT: preparing the therapeutic agent used for preventing or treating obesity, diabetes, appetite disorders and overweight.

8 cl, 1 ex

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RU 2 542 991 C2

Authors

Baroni Marko

Puleo Letitsija

Dates

2015-02-27—Published

2010-02-09—Filed