TECHNIQUE FOR DIAGNOSTICS OF HEPATIC FIBROSIS STAGES IN PATIENTS WITH CHRONIC VIRAL HEPATITIS C Russian patent published in 2016 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and aims at evaluating the state of liver in patients with chronic viral hepatitis C. Thrombocyte count in patient's whole blood is determined, and blood serum level of aspartate aminotransferase and concentration of tumour necrosis factor alpha are determined, then hepatic fibrosis index is calculated by following formula: FI=1.52-0.0047*THR+0.0091*AST+0.0429*TNF-α, if fibrosis index is in the range of 0 to 0.5, absence of fibrosis (stage F0) is determined, fibrosis index varying from 0.6 to 2.5 corresponds to moderate stage of fibrosis (F1-2), fibrosis index more than 2.5 corresponds to manifested stage of hepatic fibrosis (F3-4).

EFFECT: method allows increasing availability with high sensitivity and specificity.

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