FIELD: chemistry.
SUBSTANCE: invention relates to biologically active chemical substances. Disclosed is a silicon-boron-containing glycerohydrogel with wound-healing, regenerative and antimicrobial activity, which has formula kSi(C3H7O3)4·HB(C3H6O3)2·xC3H8O3·yH2O, where 0.5≤k≤2, 2.5≤x≤12, 20≤y≤100, obtained by reacting silicon tetraglycerolate in excess of glycerol Si(C3H7O3)4·xC3H8O3, where 2.5≤x≤14, boron biglycelorate HB(C3H6O3)2 and water in molar ratio Si(C3H7O3)4:HB(C3H6O3)2:C3H8O3:H2O, equal to (0.5÷2):1:(2.5÷12):(20÷100), at temperature of 80 °C and stirring.
EFFECT: proposed silicon-boron-containing glycerohydrogel is a physiologically active substance, non-toxic, exhibits antimicrobial, wound healing and regenerative action, improves morphofunctional condition of skin, is a convenient form for local application, widens range of medicinal agents and may be recommended for use in medical practice.
1 cl, 1 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SILICON-ZINC-BORON-CONTAINING GLYCEROGYDROGEL FOR LOCAL APPLICATION, FACILITATING FOR VULNERARY, REGENERATIVE, BACTERICIDAL AND ANTIFUNGAL ACTIVITY | 2015 |
|
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|
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| SILICON GLYCERATES ELICITING TRANSCUTANEOUS CONDUCTIVITY OF MEDICINAL AGENTS AND GLYCEROHYDROGELS BASED ON THEREOF | 2003 |
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