FIELD: pharmacology.
SUBSTANCE: invention is a silicon-zinc-boron-containing glycerogyrogel for topical application, with wound-healing, regenerative, bactericidal and antifungal activity, with composition corresponding to the formula mSi(C3H7O3)4⋅ZnC3H6O3⋅nHB(C3H6O3)2⋅xC3H8O3⋅yH2O, where 1≤m≤3, 1≤n≤2, 9≤x≤15, 28≤y≤70, obtained by interaction of silicon tetraglycerolate in an excess of glycerin Si(C3H7O3)4⋅xC3H8O3, where 1.5≤x≤4.5, zinc monoglycerolate in excess of glycerin⋅ ZnC3H6O3⋅6C3H8O3, boron bisglycerolate HB(C3H6O3)2 and water in a molar ratio of Si(C3H7O3)4:ZnC3H6O3:HB(C3H6O3)2:C3H8O3:H2O, equal to (1÷3):1:(1÷2):(9÷15):(28÷70), at a temperature of 40-60°C and stirring.
EFFECT: creation of a product that is safe to use and has a wide range of pharmacological activities - wound healing, regenerating, bactericidal and fungistatic, in a convenient form for topical application, storage stable, well reproducible in the production process using available raw materials.
2 tbl, 5 ex
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Authors
Dates
2017-06-22—Published
2015-11-24—Filed