SILICON-ZINC-BORON-CONTAINING GLYCEROGYDROGEL FOR LOCAL APPLICATION, FACILITATING FOR VULNERARY, REGENERATIVE, BACTERICIDAL AND ANTIFUNGAL ACTIVITY Russian patent published in 2017 - IPC A61K31/47 A61K31/69 A61K31/695 A61K31/315 A61P17/02 A61P31/04 A61P31/10 

Abstract RU 2623153 C2

FIELD: pharmacology.

SUBSTANCE: invention is a silicon-zinc-boron-containing glycerogyrogel for topical application, with wound-healing, regenerative, bactericidal and antifungal activity, with composition corresponding to the formula mSi(C3H7O3)4⋅ZnC3H6O3⋅nHB(C3H6O3)2⋅xC3H8O3⋅yH2O, where 1≤m≤3, 1≤n≤2, 9≤x≤15, 28≤y≤70, obtained by interaction of silicon tetraglycerolate in an excess of glycerin Si(C3H7O3)4⋅xC3H8O3, where 1.5≤x≤4.5, zinc monoglycerolate in excess of glycerin⋅ ZnC3H6O3⋅6C3H8O3, boron bisglycerolate HB(C3H6O3)2 and water in a molar ratio of Si(C3H7O3)4:ZnC3H6O3:HB(C3H6O3)2:C3H8O3:H2O, equal to (1÷3):1:(1÷2):(9÷15):(28÷70), at a temperature of 40-60°C and stirring.

EFFECT: creation of a product that is safe to use and has a wide range of pharmacological activities - wound healing, regenerating, bactericidal and fungistatic, in a convenient form for topical application, storage stable, well reproducible in the production process using available raw materials.

2 tbl, 5 ex

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RU 2 623 153 C2

Authors

Charushin Valerij Nikolaevich

Kungurov Nikolaj Vasilevich

Chupakhin Oleg Nikolaevich

Khonina Tatyana Grigorevna

Evstigneeva Natalya Petrovna

Kokhan Muza Mikhajlovna

Zilberberg Natalya Vladimirovna

Larionov Leonid Petrovich

Amineva Polina Gennadevna

Shadrina Elena Vladimirovna

Ivanenko Mariya Vladimirovna

Zyryanova Ilnara Galimovna

Polishchuk Anton Ilich

Kuznetsov Igor Dmitrievich

Dates

2017-06-22Published

2015-11-24Filed