FIELD: medicine.
SUBSTANCE: invention relates to development of drug preparations for oncological diseases treatment. Disclosed is method for detection of substances and their compounds with anticancer activity, based on reporter protein production increasing coded by recombinant replicative-defective adenovirus, in response to substances or their compositions exposure on molecular targets from protein kinase mTOR, topoisomerases I and II, histone deacetylase and unknown targets, inhibited by LY294002 and LY303511 compositions.
EFFECT: invention enables efficient detection of substances having anticancer activity, and compositions thereof.
10 cl, 4 dwg, 4 ex
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