FIELD: medicine.
SUBSTANCE: method for detection of inhibitors of suppression of Pdcd4 tumour growth suppressor in tumour cells and pLucPdcd4 genetic construct, which is a plasmid encoding a reporter protein that is a firefly luciferase chimera with a human Pdcd4 protein, is proposed.
EFFECT: group of inventions allows to identify substances with known and presumed ability to inhibit Pdcd4 suppression in tumour cells as inhibitors of suppression of Pdcd4 tumour growth suppressor.
4 cl, 4 dwg, 6 ex
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Authors
Dates
2018-01-12—Published
2016-11-14—Filed