METHOD FOR DETECTION OF TUMOUR GROWTH Pdcd4 SUPPRESSOR SUPPRESSION INHIBITORS IN TUMOUR CELLS AND pLucPdcd4 GENETIC CONSTRUCT FOR ITS IMPLEMENTATION Russian patent published in 2018 - IPC G01N33/68 C12N15/12 

Abstract RU 2640909 C1

FIELD: medicine.

SUBSTANCE: method for detection of inhibitors of suppression of Pdcd4 tumour growth suppressor in tumour cells and pLucPdcd4 genetic construct, which is a plasmid encoding a reporter protein that is a firefly luciferase chimera with a human Pdcd4 protein, is proposed.

EFFECT: group of inventions allows to identify substances with known and presumed ability to inhibit Pdcd4 suppression in tumour cells as inhibitors of suppression of Pdcd4 tumour growth suppressor.

4 cl, 4 dwg, 6 ex

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RU 2 640 909 C1

Authors

Korobko Igor Viktorovich

Shepelev Mikhail Valentinovich

Kalinichenko Svetlana Viktorovna

Dates

2018-01-12Published

2016-11-14Filed